Combining flagelliform and dragline spider silk motifs to produce tunable synthetic biopolymer fibers
نویسندگان
چکیده
منابع مشابه
Comprehensive Proteomic Analysis of Spider Dragline Silk from Black Widows: A Recipe to Build Synthetic Silk Fibers
The outstanding material properties of spider dragline silk fibers have been attributed to two spidroins, major ampullate spidroins 1 and 2 (MaSp1 and MaSp2). Although dragline silk fibers have been treated with different chemical solvents to elucidate the relationship between protein structure and fiber mechanics, there has not been a comprehensive proteomic analysis of the major ampullate (MA...
متن کاملAnalysis of repetitive amino acid motifs reveals the essential features of spider dragline silk proteins
The extraordinary mechanical properties of spider dragline silk are dependent on the highly repetitive sequences of the component proteins, major ampullate spidroin 1 and 2 (MaSp2 and MaSp2). MaSp sequences are dominated by repetitive modules composed of short amino acid motifs; however, the patterns of motif conservation through evolution and their relevance to silk characteristics are not wel...
متن کاملNanostructure and molecular mechanics of spider dragline silk protein assemblies.
Spider silk is a self-assembling biopolymer that outperforms most known materials in terms of its mechanical performance, despite its underlying weak chemical bonding based on H-bonds. While experimental studies have shown that the molecular structure of silk proteins has a direct influence on the stiffness, toughness and failure strength of silk, no molecular-level analysis of the nanostructur...
متن کاملSpider Dragline Silk Molecular Properties and Recombinant Expression
Rising, A. 2007. Spider dragline silk – molecular properties and recombinant production. Doctor’s dissertation. ISSN: 1652-6880, ISBN: 978-91-576-7337-4 Spider dragline silk possesses several desirable features of a biomaterial; it has extraordinary mechanical properties, is biocompatible and biodegradable. It consists of large proteins, major ampullate spidroins (MaSp:s), that contain alternat...
متن کاملSupercontraction forces in spider dragline silk depend on hydration rate.
Spider dragline silk is a model biological polymer for biomimetic research due to its many desirable and unusual properties. 'Supercontraction' describes the dramatic shrinking of dragline silk fibers when wetted. In restrained silk fibers, supercontraction generates substantial stresses of 40-50 MPa above a critical humidity of approximately 70% relative humidity (RH). This stress may maintain...
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ژورنال
عنوان ژورنال: Biopolymers
سال: 2011
ISSN: 0006-3525
DOI: 10.1002/bip.21724